Thermo Fisher Scientific SORL1 Recombinant Rabbit Monoclonal Antibody (JE35-52)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JE35-52

Immunogen

Recombinant protein within Human SorLA aa 1341-1540/2214. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SORL1,uniProtId:Q92673-1,ncbiNodeId:9606,antigenRange:1341-1540,antigenLength:2214,antigenImageFileName:MA5-50824_SORL1_Q92673-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50824_SORL1_Q92673-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 0.05% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3093799

Product Specific Information

Positive control: Jurkat cell lysates, mouse cerebellum tissue, rat cerebellum tissue.

Predicted band size: 248 kDa

Subcellular Location: Cell membrane, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Secreted.

Target Information

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 domain-containing receptor family, and the low density lipoprotein receptor family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer`s Disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.