Thermo Fisher Scientific REEP5 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000 dilution

Product Specifications

Product Specific Information

This antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as confirmed by SDS-PAGE.

Target Information

REEP5 (Receptor Expression-Enhancing Protein 5), also known as C5orf18, DP1, TB2, or D5S346, is a 189-amino-acid multi-pass membrane protein. It is thought to promote the functional cell surface expression of olfactory receptors. REEP5 belongs to the DP1 family and is encoded by a gene located on chromosome 5, which spans approximately 181 million base pairs and encodes around 1,000 genes (about 6% of human genomic DNA).

Chromosome 5 is associated with several genetic conditions:

• Cockayne syndrome (ERCC8 gene)
• Familial adenomatous polyposis (APC tumor suppressor gene)
• Treacher Collins syndrome (TCOF1 gene mutations)
• Cri du chat syndrome (deletion of chromosome 5p)
• Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (deletion of 5q or entire chromosome 5)

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.