Thermo Fisher Scientific PXN Monoclonal Antibody (OTI8C12), TrueMAB
PXN 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. Human Paxillin 전장 단백질을 면역원으로 사용하였으며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능하며 -20°C에서 보관하십시오.
- 카탈로그번호
- TA811259
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C12 |
| Immunogen | Full length human recombinant protein of human PXN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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