Thermo Fisher Scientific IGF2BP3 Polyclonal Antibody
IGF2BP3 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, PBS와 sucrose buffer에 보관됩니다. 악성 흑색종 등 암 연구용으로 활용됩니다.
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Applications
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human IGF2BP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610519 |
Product Specific Information
Peptide sequence:
KEGATIRNIT KQTQSKIDVH RKENAGAAEK SITILSTPEG TSAACKSILE
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family. It is expressed during embryogenesis and in certain malignancies.
IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present. It is found in a significantly higher proportion of melanomas than Spitz nevi and is more abundant in metastatic melanomas compared to thin melanomas.
IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in regulating the biological behavior of this tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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