Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI17C1), TrueMAB
인간 GPR17 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 IHC(P)에서 사용 가능. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제. 액상 형태, PBS/BSA/glycerol 버퍼에 저장되며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:150–1:600
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI17C1 |
| Immunogen | Synthetic peptide within Human GPR17 C-terminal (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily includes an estimated 600–1,000 members and represents the largest known class of molecular targets with proven therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in the orchestration of oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase, possibly mediating brain damage following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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