Thermo Fisher Scientific ARNT2 Polyclonal Antibody
ARNT2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 ELISA에 적합하며, 마우스와 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol 완충액에 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 440–690 of human ARNT2 (NP_055677.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854824 |
Product Specific Information
Immunogen sequence:
QLQQQQAELE VHQRDGLSSY DLSQVPVPNL PAGVHEAGKS VEKADAIFSQ ERDPRFAEMF AGISASEKKM MSSASAAGTQ QIYSQGSPFP SGHSGKAFSS SVVHVPGVND IQSSSSTGQN MSQISRQLNQ SQVAWTGSRP PFPGQQIPSQ SSKTQSSPFG IGTSHTYPAD PSSYSPLSSP ATSSPSGNAY SSLANRTPGF AESGQSSGQF QGRPSEVWSQ WQSQHHGQQS GEQHSHQQPG QTEVFQDMLP M
Target Information
AhR, ARNT1, ARNT2, and BMAL1 are members of a family of transcription factors containing a basic helix-loop-helix motif and a common PAS motif.
The aromatic hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that binds xenobiotic responsive elements (XREs) to activate genes such as CYP1A1, glutathione S-transferase Ya subunit, and DT-diaphorase.
Ah receptor nuclear translocator proteins (Arnt1 or Arnt2) are required for ligand-dependent nuclear translocation of AhR and its binding to the XRE element.
BMAL1 (Brain and Muscle Arnt-like protein 1), also known as Arnt3, TIC, JAP3, or MOP-3, dimerizes with Clock and binds to the promoter region of mPer1, playing a role in circadian rhythm regulation in mammals.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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