Thermo Fisher Scientific ARNT2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
QLQQQQAELE VHQRDGLSSY DLSQVPVPNL PAGVHEAGKS VEKADAIFSQ ERDPRFAEMF AGISASEKKM MSSASAAGTQ QIYSQGSPFP SGHSGKAFSS SVVHVPGVND IQSSSSTGQN MSQISRQLNQ SQVAWTGSRP PFPGQQIPSQ SSKTQSSPFG IGTSHTYPAD PSSYSPLSSP ATSSPSGNAY SSLANRTPGF AESGQSSGQF QGRPSEVWSQ WQSQHHGQQS GEQHSHQQPG QTEVFQDMLP M

Target Information

AhR, ARNT1, ARNT2, and BMAL1 are members of a family of transcription factors containing a basic helix-loop-helix motif and a common PAS motif.
The aromatic hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that binds xenobiotic responsive elements (XREs) to activate genes such as CYP1A1, glutathione S-transferase Ya subunit, and DT-diaphorase.
Ah receptor nuclear translocator proteins (Arnt1 or Arnt2) are required for ligand-dependent nuclear translocation of AhR and its binding to the XRE element.
BMAL1 (Brain and Muscle Arnt-like protein 1), also known as Arnt3, TIC, JAP3, or MOP-3, dimerizes with Clock and binds to the promoter region of mPer1, playing a role in circadian rhythm regulation in mammals.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.