Thermo Fisher Scientific RAD17 Polyclonal Antibody
RAD17 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 389-681 아미노산 영역의 재조합 단백질을 면역원으로 사용했습니다. 세포 성장 유지, DNA 손상 반응 연구에 활용됩니다. 0.62 mg/mL 농도의 액상 형태로 제공되며, 4°C 또는 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 389–681 of Rad17 (Uniprot ID: O75943) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2551980 |
Product Specific Information
- Recommended positive controls: 293T
- Predicted reactivity: Mouse (84%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. It may also serve as a sensor of DNA replication progression and may be involved in homologous recombination.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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