Thermo Fisher Scientific Human Ferritin Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state.

Defects in the light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. The ferritin gene has multiple pseudogenes, and ferritin is a ubiquitous and highly conserved protein that plays a major role in iron homeostasis.

Ferritin is a holoenzyme shell with a molecular weight of about 450 kDa, consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.