Thermo Fisher Scientific ACVR2B Polyclonal Antibody
ACVR2B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Mouse 반응성 확인. Western blot과 IHC(P) 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:50,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–323 of Human Activin Receptor Type IIB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545707 |
Product Specific Information
- Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, mouse cerebellum, mouse testis, ACVR2B-transfected 293T
- Predicted reactivity: Mouse (99%), Rat (99%), Pig (100%), Chicken (89%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-28231_ACVR2B_Q13705-1_Rabbit.svg, PA5-28231_ACVR2B_Q13705-1_Rabbit_PDP.jpeg)
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