Thermo Fisher Scientific CSH2 Polyclonal Antibody

Thermo Fisher Scientific CSH2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A549, H1299, HCT116, MCF-7
• Predicted reactivity: Chimpanzee (97%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control.
The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement thought to have evolved by gene duplication.
Although the five genes share a high degree of sequence identity, they are expressed selectively in different tissues.
Alternative splicing generates additional isoforms of each of the five growth hormones.
This family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites.
Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term.
Structural and expression differences provide avenues for developmental regulation and tissue specificity.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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