Thermo Fisher Scientific ARK1C2 Polyclonal Antibody
ARK1C2 단백항체로 Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 Rabbit Polyclonal IgG. PBS 완충액에 0.01% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | FNHRLLEMIC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: HeLa lysate
Target Information
DD1 is also designated AKR1C1, DDH or DDH1, while DD2 also can be designated AKR1C2, dDD, BABP or DDH2.
AKR1C3 and 3 alpha-HSD are alternate designations for human DD3 (AKR1C18 in rodents), while DD4 can be called AKR1C4, CD, CHDR or AKR1C6 (in rodents).
DD1 and DD2 are 20 alpha-HSDs, whereas DD3 and DD4 are 3 alpha-HSDs.
The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics such as polycyclic aromatic hydrocarbons, pesticides, and steroid hormones, and are responsible for the reduction of ketone-containing drugs using NADH or NADPH as a cofactor.
The 20 alpha-HSD catalyzes the reaction of progesterone to the inactive form 20 alpha-hydroxyprogesterone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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