Thermo Fisher Scientific HPV-18 (Human Papilloma Virus 18) Monoclonal Antibody (HPV18/1297)
HPV18 E6 단백질을 인식하는 Mouse Monoclonal Antibody로, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 고순도 Protein A/G 정제, 200 µg/mL 농도, PBS 기반 저장액 포함. 연구용으로 바이러스성 암 연구에 활용됩니다.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HPV18/1297 |
| Immunogen | HPV18 E6-β-galactosidase fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women and accounts for a high mortality rate due to late diagnosis and poor prognosis.
Initial establishment and subsequent progression of this cancer type are completely dependent on two major oncogenes, E6 and E7, which are constitutively expressed and lead to tumorigenesis.
E6 is a relatively large protein with 150–160 amino acids coding an 18 kDa protein. Its unique structure has been found responsible for the oncogenicity of the protein.
[PMID: 32038557]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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