Thermo Fisher Scientific HPV-18 (Human Papilloma Virus 18) Monoclonal Antibody (HPV18/1297)
HPV18 E6 단백질을 인식하는 마우스 단일클론 항체로, 면역조직화학(IHC) 실험에 적합합니다. 단백질 A/G로 정제된 액상형 비결합 항체이며, 바이러스 연구용으로 사용됩니다. 연구 전용 제품으로 진단용은 아닙니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HPV18/1297 |
| Immunogen | HPV18 E6-β-galactosidase fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women and accounts for a high mortality rate due to late diagnosis and poor prognosis.
The initial establishment and subsequent progression of this cancer type are completely dependent on two major oncogenes, E6 and E7, which are constitutively expressed and lead to tumorigenesis.
E6 is a relatively large protein consisting of 150–160 amino acids, encoding an 18 kDa protein. Its unique structure has been found responsible for the oncogenicity of the protein.
[PMID: 32038557]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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