Thermo Fisher Scientific RAB21 Polyclonal Antibody
RAB21 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 래빗 IgG 항체. Western blot 및 IHC(P) 실험에 적합하며, 인간·마우스·랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB21 (Accession Q9UL25), corresponding to amino acid residues V142–G192 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853397 |
Product Specific Information
Antibody detects endogenous levels of total RAB21.
Target Information
RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting.
In non-polarized Caco-2 cells, RAB21 shows a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localizes to apical vesicles.
RAB21 associates with integrin subunits and is important for receptor entry into cells via RAB5/RAB21 endosomes.
The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the alpha-tail of endocytosed integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-104068_RAB21_Q9UL25-1_Rabbit_PDP.jpeg)
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