
Thermo Fisher Scientific RAB1B Polyclonal Antibody
RAB1B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용 가능. ER-Golgi 간 소포 수송 및 자가포식 관련 연구에 적합. 고순도 Affinity chromatography 정제 및 안정적 PBS/glycerol 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB1B (Accession Q9H0U4), corresponding to amino acid residues T72–K122 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853396 |
Product Specific Information
Antibody detects endogenous levels of total RAB1B.
Target Information
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that recruits downstream effectors responsible for vesicle formation, movement, tethering, and fusion.
RAB1B regulates vesicular transport between the endoplasmic reticulum (ER) and successive Golgi compartments. It also plays a role in the initial events of autophagic vacuole development occurring at specialized regions of the ER.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-104067_RAB1B_Q9H0U4-1_Rabbit.svg, PA5-104067_RAB1B_Q9H0U4-1_Rabbit_PDP.jpeg)
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