Thermo Fisher Scientific RASA1 Polyclonal Antibody
Human RASA1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 1 mg/mL 액상 형태로 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- A305-647A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 997 to 1047 of human Ras GTPase-activating protein 1 (RasGAP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted reactivity by homology: Rat, Bovine.
Target Information
TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members (TACC1, TACC2, TACC3) map closely to FGFR1, FGFR2, and FGFR3 genes on chromosomes 4, 8, and 10. Since they are phylogenetically related, TACC and FGFR are proposed to have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region similar to the Drosophila homolog D-TACC, which is necessary for normal spindle function. Mammalian TACC proteins interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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