Thermo Fisher Scientific ATP6V1D Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total ATP6V1D.

Target Information

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for intracellular processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.

V-ATPase is composed of:

• V1 domain: three A and three B subunits, two G subunits, plus C, D, E, F, and H subunits (contains ATP catalytic site)
• V0 domain: five subunits (a, c, c’, c”, and d)

Additional isoforms of many V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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