Thermo Fisher Scientific APLP1 Recombinant Rabbit Monoclonal Antibody (3U2I7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

3U2I7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 470-580 of human APLP1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:APLP1,uniProtId:P51693-1,ncbiNodeId:9606,antigenRange:470-580,antigenLength:650,antigenImageFileName:MA5-55388_APLP1_P51693-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55388_APLP1_P51693-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: NPHLAQELRP QIQELLHSEH LGPSELEAPA PGGSSEDKGG LQPPDSKDDT PMTLPKGSTE QDAASPEKEK MNPLEQYERK VNASVPRGFP FHSSEIQRDE LAPAGTGVSR E

Target Information

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.