Thermo Fisher Scientific APLP1 Recombinant Rabbit Monoclonal Antibody (3U2I7)
Recombinant rabbit monoclonal antibody targeting human APLP1. Validated for WB and ELISA. Expressed in HEK293 cells and purified via Protein A. Supplied as liquid in PBS with glycerol and BSA. For research use only.
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- MA555388
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3U2I7 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 470–580 of human APLP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
NPHLAQELRP QIQELLHSEH LGPSELEAPA PGGSSEDKGG LQPPDSKDDT PMTLPKGSTE QDAASPEKEK MNPLEQYERK VNASVPRGFP FHSSEIQRDE LAPAGTGVSR E
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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