Thermo Fisher Scientific ATP6V0C Recombinant Rabbit Monoclonal Antibody (3C7J3)
ATP6V0C 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제되었습니다. 인간 시료에 반응하며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3C7J3 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human ATP6V0C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MSESKSGPEY ASFFAVMGAS AAMVFSALGA AYGTAKSGTG IAAMSVMRPE QIMKSIIPVV MAGIIAIYGL VVAVLIANSL NDDISLYKSF LQLGAGLSVG
Target Information
ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase–dependent organelle acidification is necessary for intracellular processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain includes three A and three B subunits, two G subunits, and the C, D, E, F, and H subunits, containing the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c′, c″, and d. ATP6V0C encodes the V0 subunit c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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