Thermo Fisher Scientific Ku80 Polyclonal Antibody
Ku80 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow, IP 등 다양한 응용에 사용 가능. 인간, 마우스, 비인간 영장류 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. DNA 복구 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 | - |
| Immunocytochemistry (ICC/IF) | 1:400 | - |
| Flow Cytometry (Flow) | 1:50 | - |
| Immunoprecipitation (IP) | 1:25 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the carboxy terminus of mouse Ku80 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 26 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986109 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5.
Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks via non-homologous end joining and V(D)J recombination.
This gene complements the Chinese hamster xrs-6 mutant defective in DNA double-strand break repair and V(D)J recombination.
A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-17454_Ku80_P27641-1_Rabbit.svg, PA5-17454_Ku80_P27641-1_Rabbit_PDP.jpeg)
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