Thermo Fisher Scientific AMPK gamma-3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human AMPK gamma-3 subunit. Validated for Western blot at 1:1,000 dilution. Affinity purified and supplied in liquid form. Suitable for energy metabolism and AMPK pathway research. For research use only.
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Applications and Tested Dilution
- Application: Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the sequence of human AMPK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984837 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK acts as an energy sensor that monitors cellular energy status. Under metabolic stress, AMPK becomes activated and phosphorylates key enzymes such as acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), which regulate fatty acid and cholesterol biosynthesis. The gamma-3 subunit is predominantly expressed in skeletal muscle and may play a key role in energy metabolism regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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