Thermo Fisher Scientific XRCC3 Monoclonal Antibody (10F1/6)
인체 XRCC3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(PFA 고정)에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관. DNA 손상 복구 연구 및 염색체 안정성 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F1/6 |
| Immunogen | Recombinant full-length human XRCC3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The XRCC3 gene encodes a member of the RecA/Rad51-related protein family involved in homologous recombination to maintain chromosome stability and repair DNA damage. This gene complements repair-deficient mutants such as Chinese hamster irs1SF, which show hypersensitivity to DNA-damaging agents and chromosomal instability. A rare microsatellite polymorphism in XRCC3 is linked to cancer susceptibility and radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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