Thermo Fisher Scientific DOT5 Polyclonal Antibody
Thermo Fisher Scientific DOT5 Polyclonal Antibody는 효모 DOT5 단백질을 인식하는 토끼 IgG 항체로, Western blot 및 ELISA에 적합합니다. 단백질 G 정제, 액상 형태이며, 산화 스트레스 관련 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
ELISA
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) DOT5 protein (37–118aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.9 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3091708 |
Target Information
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure leading to transcriptional stop of nearby genes, and in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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