Thermo Fisher Scientific TIP60 Polyclonal Antibody
TIP60 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스 반응성 확인. Western blot에 1:1000 희석으로 사용 가능. DNA 복구 및 전사 조절 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 33–64 amino acids from the N-terminal region of human KAT5 / Tip60 / HTATIP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2249295 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
TIP60 is a transcription factor originally isolated as an HIV-1 TAT-interactive protein. It interacts with the viral TAT protein, leading to HTATIP polyubiquitination and degradation. Belonging to the MYST family of histone acetyltransferases (HATs), TIP60 serves as a catalytic subunit of the NuA4 histone acetyltransferase complex, which activates transcription of specific genes through acetylation of nucleosomal histone H4 and H2A. As a co-regulator of transcription factors, TIP60 can either promote or suppress tumorigenesis. It plays roles in DNA repair, apoptosis, and signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-11216_TIP60_Q92993-1_Rabbit.svg
- PA5-11216_TIP60_Q92993-1_Rabbit_PDP.jpeg
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