Thermo Fisher Scientific P-Glycoprotein Recombinant Rabbit Monoclonal Antibody (23GB1330)
P-Glycoprotein(ABCB1)을 인식하는 재조합 토끼 단클론 항체로, Western blot과 Immunocytochemistry에 적합합니다. HEK293F 발현 시스템에서 생산되었으며, 액상 형태로 제공됩니다. 인간, 마우스, 랫트 시료에 반응하며 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1330 |
| Immunogen | A synthesized peptide derived from human P-Glycoprotein (350–750 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The membrane-associated protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein, a member of the MDR/TAP subfamily, functions as an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It plays a key role in multidrug resistance by reducing intracellular drug accumulation and contributes to resistance against anticancer drugs. It also serves as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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