Thermo Fisher Scientific APC11 Monoclonal Antibody (6F1G9)
인간 ANAPC11 단백질을 인식하는 마우스 단클론 항체로, Western blot, Flow cytometry, ELISA에 적합합니다. Protein G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 세포주기 조절 연구용으로 사용되며, 연구용으로만 제공됩니다.
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Thermo Fisher Scientific APC11 Monoclonal Antibody (6F1G9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F1G9 |
| Immunogen | Purified recombinant fragment of human ANAPC11 (AA: 1–196) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090953 |
Target Information
Together with the cullin protein ANAPC2, APC11 constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
The APC/C complex mediates ubiquitination and subsequent degradation of target proteins, primarily forming Lys-11-linked polyubiquitin chains and, to a lesser extent, Lys-48- and Lys-63-linked polyubiquitin chains. It may recruit E2 ubiquitin-conjugating enzymes to the complex.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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