Thermo Fisher Scientific LCLAT1 Polyclonal Antibody
LCLAT1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 고농도(1 mg/mL) 액상 형태로 연구용에 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LCLAT1 (amino acids 261–360) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LCLAT1 exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity, catalyzing the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling. It recognizes both monolysocardiolipin and dilysocardiolipin as substrates, with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors.
Also shows 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT) activity, converting lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Possesses lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Required for establishment of hematopoietic and endothelial lineages.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: BS-18190R_LCLAT1_Q6UWP7-1_Rabbit_PDP.jpeg, BS-18190R_LCLAT1_Q6UWP7-1_Rabbit.svg)
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