Thermo Fisher Scientific AP2M1 Monoclonal Antibody (OTI1C8), TrueMAB
AP2M1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot 및 Immunocytochemistry에 적합합니다. Human, Mouse, Rat, Dog 반응성을 보이며, 고순도 Affinity Chromatography 정제 및 안정적인 PBS/BSA/Glycerol buffer로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Human recombinant protein fragment (aa 97–383 of human AP2M1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family.
The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, responsible for proton pumping during endosome and lysosome acidification.
AP2M1 associates with the HIV-1 protein Nef, suggesting that Nef may use the AP-2 complex to enhance endocytosis of CD4 and class I MHC.
It may also regulate intracellular trafficking and function of CTLA-4 protein.
At least two isoforms of AP2M1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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