Thermo Fisher Scientific PRPF8 Polyclonal Antibody
PRPF8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 고순도 액상형으로 1 mg/mL 농도, 4°C 보관. FFPE 조직에서 citrate buffer(pH 6.0)로 epitope retrieval 권장.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2285 and 2335 of Human Pre-mRNA-Processing Factor 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes and is essential for the catalytic step II in the pre-mRNA splicing process. It contains several WD repeats that function in protein–protein interactions. This protein shows sequence similarity to yeast Prp8 protein. The gene is a candidate for autosomal dominant retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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