Thermo Fisher Scientific PSG1 Polyclonal Antibody
PSG1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%) 제품으로 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 180–419 of human PSG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803967 |
Product Specific Information
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin. PSGs are also expressed in trophoblast-origin tumors such as hydatidiform mole and choriocarcinoma. They are the most abundant fetal proteins in maternal blood at term. The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes, with CD9 identified as the monocyte receptor for murine PSG17. PSGs are thought to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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