Thermo Fisher Scientific COX6C Polyclonal Antibody
Human COX6C 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장액과 40% 글리세롤 포함. 미토콘드리아 전자전달 효소 복합체 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COX6C. Recombinant protein control fragment (Product #RP-102541) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640102 |
Product Specific Information
- Immunogen sequence: EPRKKAYADF YRNYDVMKDF EDMRKTGT
- Highest antigen sequence identity to orthologs:
- Mouse: 82%
- Rat: 82%
Target Information
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may be involved in regulation and assembly of the complex.
This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. The gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosome 16p12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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