Thermo Fisher Scientific CARD9 Polyclonal Antibody
CARD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human 시료 반응성, Protein A 정제, 고농도(1 mg/mL) 액상 형태. 세포 사멸 및 NF-κB 신호 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CARD9, amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). This domain mediates protein-protein interactions involved in activation or suppression of caspase family members, playing a key role in apoptosis regulation. CARD9 selectively associates with the CARD domain of BCL10, a positive regulator of apoptosis and NF-κB activation, and acts as a molecular scaffold for assembling the BCL10 signaling complex that activates NF-κB. Several alternatively spliced transcript variants have been identified, though their full-length forms are not fully defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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