Thermo Fisher Scientific KPNA2 Polyclonal Antibody
KPNA2 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등에 사용 가능. 인간과 랫트 반응성, 액상 형태, 0.5 mg/mL 농도. 핵 단백질 수입 관련 연구에 적합.
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Thermo Fisher Scientific KPNA2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QVQDGAPGTFNF) corresponding to the C-terminus amino acids of KPNA2 (aa 518–529) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980060 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The import of proteins into the nucleus involves two steps:
- Energy-independent docking of the protein to the nuclear envelope.
- Energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), typically consisting of one or two short regions of basic amino acids. Proteins involved in nuclear import include Xenopus importin and its yeast homolog SRP1, which bind to the NLS.
KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in nuclear transport and VJ recombination.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-18237_KPNA2_P52292-1_Goat.svg, PA5-18237_KPNA2_P52292-1_Goat_PDP.jpeg)
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