Thermo Fisher Scientific PIST Polyclonal Antibody
Thermo Fisher Scientific의 PIST Polyclonal Antibody는 인간 GOPC 단백질을 인식하는 염소 유래 IgG 항체입니다. Western blot 및 ICC/IF에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용되며 -20°C에서 보관하십시오.
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Applications
Western Blot (WB)
- Tested Dilution: 0.05–0.2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (LDDLHTLYHKKSY) corresponding to the C-terminus amino acids of GOPC (aa 450–462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983764 |
Product Specific Information
- This antibody is predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.
PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6.
Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-18240_PIST_Q9HD26-1_Goat.svg)
(이미지: PA5-18240_PIST_Q9HD26-1_Goat_PDP.jpeg)
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