Thermo Fisher Scientific Dectin 1 (soluble) Monoclonal Antibody (2A11), PE

Applications and Tested Dilution

Product Specifications

Additional Formats

• Unconjugated (Cat. MA5-16477)
• FITC (Cat. MA5-16479)
• Custom conjugation available upon request

Product Specific Information

• Reconstitute with 1 mL of distilled water.
• After reconstitution, store undiluted at 4°C in the dark.
• Shelf life after reconstitution: approximately 18 months.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
• Rat anti-Mouse Dectin-1 antibody, clone 2A11, recognizes murine beta-glucan receptor (Dectin-1).

Target Information

CLEC7A (Dectin-1) is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily, predominantly expressed on myeloid cells. It functions as a pattern-recognition receptor that binds beta-1,3- and beta-1,6-linked glucans from fungi and plants, playing a critical role in innate immunity. Upon fungal recognition, CLEC7A activates Syk tyrosine kinase, inducing reactive oxygen species formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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