Thermo Fisher Scientific KLC1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains that transport various cargos along microtubules toward their plus ends.
The heavy chains provide motor activity, while the light chains bind to cargos.
This gene encodes a member of the kinesin light chain family, which associates with kinesin heavy chain through an N-terminal domain.
Six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding cargos such as vesicles, mitochondria, and the Golgi complex.
Kinesin light chains act as adapter molecules rather than motors.
Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily.
Extensive alternative splicing produces isoforms with different C-termini proposed to bind to different cargos; however, the full-length nature of some variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.