Thermo Fisher Scientific GIPR Chimeric Recombinant Rabbit Monoclonal Antibody (Gipg013)
GIPR 단백질을 인식하는 재조합 토끼 단클론 항체로, ICC/IF, ELISA, 억제 분석 등에 사용 가능. 인간, 마우스, 랫, 개에 반응하며 HEK293 세포에서 발현. 높은 특이성과 재현성 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
| ELISA | Assay-dependent | - |
| Inhibition Assays (IA) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Gipg013 |
| Immunogen | Human GIPr |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074396 |
Product Specific Information
Specificity: The original antibody has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
Target Information
GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release. It was later shown to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defects in this gene may contribute to the pathogenesis of diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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