Thermo Fisher Scientific Ficolin 3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human FCN3 (aa 35-84). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ficolin 3,uniProtId:O75636-1,ncbiNodeId:9606,antigenRange:35-84,antigenLength:299,antigenImageFileName:PA5-42017_Ficolin_3_O75636-1_Rabbit.svg,antigenImageFileNamePDP:PA5-42017_Ficolin_3_O75636-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2610026

Product Specific Information

Peptide sequence: LEASKVVLLP SCPGAPGSPG EKGAPGPQGP PGPPGKMGPK GEPGDPVNLL

Sequence homology: Cow: 91%; Dog: 79%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 91%; Pig: 91%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%

Target Information

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.