Thermo Fisher Scientific SFTPC Polyclonal Antibody
SFTPC 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, SPR 등 다양한 분석에 적합합니다. 인간 시료에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Surface Plasmon Resonance (SPR) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SFTPC (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609488 |
Product Specific Information
Peptide sequence:
MDVGSKEVLM ESPPDYSAAP RGRFGIPCCP VHLKRLLIVV VVVVLIVVVI
Sequence homology:
Dog: 100%
Guinea Pig: 86%
Horse: 100%
Human: 100%
Mouse: 79%
Rabbit: 100%
Rat: 100%
Sheep: 85%
Target Information
The SFTPC gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins, including plasma proteins and apolipoproteins SPA, SPB, SPC, and SPD. It is secreted by alveolar cells and maintains pulmonary tissue stability by reducing surface tension of fluids coating the lungs.
Mutations in this gene can cause pulmonary surfactant metabolism dysfunction type 2 (also known as pulmonary alveolar proteinosis due to surfactant protein C deficiency) and are associated with interstitial lung disease in infants, children, and adults.
Alternatively spliced transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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