Thermo Fisher Scientific Caspase 6 Monoclonal Antibody (3B7E10)
인간 Caspase 6 단백질을 인식하는 마우스 단클론 항체입니다. Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능합니다. 고순도 Protein G 정제, 1 mg/mL 농도, 장기 보관 시 -20°C에서 안정적입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B7E10 |
| Immunogen | Purified recombinant fragment of human CASP6 (AA: 194–293) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3091349 |
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are divided into initiator caspases (activated by receptor clustering, e.g., Caspase-8 and Caspase-9) and effector caspases (activated by mitochondrial permeability transition, e.g., Caspase-3 and Caspase-7). Initiator caspases activate effector caspases, leading to cell collapse and apoptosis progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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