Thermo Fisher Scientific P-Selectin/CD62P Recombinant Rabbit Monoclonal Antibody (BLR267L)
Thermo Fisher의 P-Selectin/CD62P 재조합 Rabbit Monoclonal Antibody (BLR267L)은 인간 P-Selectin을 특이적으로 인식하며, WB, IHC, ICC/IF에 적합합니다. 고순도 액상 형태로 제공되며, 4°C에서 안정적으로 보관 가능합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR267L |
| Immunogen | Recombinant protein representing the extracellular domain of Human P-Selectin/CD62P (residues 42–771) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Product is tested in Multiplex Immunofluorescence (mIF).
Target Information
P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type I transmembrane glycoprotein involved in cell adhesion and rolling. It is stored in the Weibel-Palade bodies of endothelial cells and α-granules of platelets, and rapidly translocates to the cell surface upon activation by thrombin, histamine, complement 5a, Ca²⁺ ionophores, or ADP.
P-selectin mediates interactions between activated endothelial cells or platelets and leukocytes, acting as a calcium-dependent receptor that binds sialylated Lewis carbohydrate antigens on neutrophils and monocytes.
It plays a key role in inflammation, atherogenesis, thrombosis, and tissue destruction. Clinically, P-selectin is used to help distinguish heparin-induced thrombocytopenia with and without thrombosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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