Thermo Fisher Scientific CSNK1G1 Monoclonal Antibody (2E10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

2E10

Immunogen

CSNK1G1 (AAH17236, 293 a.a. approximately 393 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CK1 gamma-1,uniProtId:Q9HCP0-1,ncbiNodeId:9606,antigenRange:293-393,antigenLength:422,antigenImageFileName:H00053944-M02_CK1_gamma-1_Q9HCP0-1_House_mouse.svg,antigenImageFileNamePDP:H00053944-M02_CK1_gamma-1_Q9HCP0-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: KKGYTFDYAY DWVGRPIPTP VGSVHVDSGA SAITRESHTH RDRPSQQQPL RNQVVSSTNG ELNVDDPTGA HSNAPITAHA EVEVVEEAKC CCFFKRKRKK T

Target Information

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha` beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.