Thermo Fisher Scientific AMPK gamma-1,2,3 Polyclonal Antibody
AMPK gamma-1,2,3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human, Mouse, Rat 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKAG1 (Accession P54619), corresponding to amino acid residues K58–E108 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850575 |
Product Specific Information
Antibody detects endogenous levels of total PRKAG1/2/3.
Target Information
The 5-AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non-fermentor) kinase family, is a heterotrimeric protein composed of alpha (63 kDa), beta (30 kDa), and gamma (38 kDa) subunits.
- Alpha subunit: catalytic
- Beta and gamma subunits: non-catalytic but interact with the active subunit in liver
AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA carboxylase, and cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase.
AMPK is activated by AMP and can also be regulated by treatment with purified protein phosphatase in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 이미지 파일: PA5-101131_AMPK_gamma-1,2,3_P54619-1_Rabbit.svg / PA5-101131_AMPK_gamma-1,2,3_P54619-1_Rabbit_PDP.jpeg)
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