Thermo Fisher Scientific ZIP14 Polyclonal Antibody
ZIP14 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응하며, Affinity Chromatography로 정제됨. 세포막 및 lamellipodium에서 ZIP14 발현 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acids 101–200 of human ZIP14 (NP_001121903.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804476 |
Product Specific Information
- Positive Samples: LO2, HeLa
- Cellular Location: Cell membrane, Cell projection, Multi-pass membrane protein, lamellipodium
- Immunogen sequence: EENEQTEEGR PSAVE
Target Information
The zinc transporter ZIP14 (SLC39A14) is a member of the divalent ion transporter family. Zinc is essential for cellular growth, development, and differentiation. The zinc transporter family includes four subfamilies: I, II, LIV-1, and gufA.
ZIP14 is a glycosylated multipass plasma membrane protein belonging to the LIV-1 subfamily. It contributes to hypozincemia during inflammation and infection and is regulated in the liver by IL-6.
ZIP14 also mediates the uptake of non–transferrin-bound iron and iron bound to transferrin.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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