Thermo Fisher Scientific AP3M1 Polyclonal Antibody
Thermo Fisher Scientific의 AP3M1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot 및 ELISA에 사용 가능합니다. Rabbit IgG 폴리클로날 항체로, PBS와 50% 글리세롤에 보관되며 -20°C에서 안정적입니다. 골지체 및 세포질막 단백질 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 219–418 of human AP3M1 (NP_0362271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.78 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804474 |
Product Specific Information
Immunogen sequence:
SLSFMNPRLL DDVSFHPCIR FKRWESERVL SFIPPDGNFR LISYRVSSQN LVAIPVYVKH SISFKENSSC GRFDITIGPK QNMGKTIEGI TVTVHMPKVV LNMNLTPTQG SYTFDPVTKV LTWDVGKITP QKLPSLKGLV NLQSGAPKPE ENPSLNIQFK IQQLAISGLK VNRLDMYGEK YKPFKGVKYV TKAGKFQVRT
Positive Samples:
22Rv1, Mouse liver, Mouse kidney, Rat spinal cord, Rat liver
Cellular Location:
Cytoplasmic side, Cytoplasmic vesicle membrane, Golgi apparatus, Peripheral membrane protein
Target Information
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2), and a small adaptin (APS1 or AP3S2).
This complex is associated with the Golgi region and peripheral structures, facilitating vesicle budding from the Golgi membrane and trafficking to lysosomes.
AP3M1 is highly homologous to AP3M2 but preferentially binds the YQRL motif from the cytosolic domain of TGN38 and interacts with the HIV-1 virulence protein Nef.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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