ELK Biotechnology CCDC102B rabbit pAb
CCDC102B 단백질에 특이적인 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인체 유래 합성 펩타이드로 면역화되었으며, 60kDa 밴드 검출. 사람, 쥐, 생쥐 시료에 반응하며 -20°C에서 1년 보관 가능.
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CCDC102B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | CCDC102B rabbit pAb |
| Alternative Names | CCDC102B; C18orf14; Coiled-coil domain-containing protein 102B |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CCDC102B (AA range: 81–130) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kDa |
| Gene ID (Human) | 79839 |
| Human Swiss-Prot No. | Q68D86 |
| Species Reactivity | Human; Rat; Mouse |
Background
CCDC102B (coiled-coil domain containing 102B), also known as AN, ACY1L or HsT1731, is a 513 amino acid protein that exists as three alternatively spliced isoforms. It is widely expressed and located in multiple CNV regions. CCDC102B contains the deletion breakpoint of a maternally inherited 2.7 Mb deletion mapping to human chromosome 18q22.1. It may be involved in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma, and schizophrenia. Chromosome 18 encodes over 300 genes and spans approximately 76 million bases. Translocation between chromosomes 18 and 14 is common in cancers, particularly follicular lymphomas. Diseases such as Niemann-Pick disease, hereditary hemorrhagic telangiectasia, and erythropoietic protoporphyria are associated with chromosome 18.
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