ELK Biotechnology Caspase-6 rabbit pAb
Caspase-6 rabbit pAb는 인간, 마우스, 랫트에 반응하는 폴리클로날 항체로, 세포사멸 관련 단백질 분석에 적합합니다. WB, IHC, IF, ELISA 등 다양한 응용에 사용 가능하며, 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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Caspase-6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Caspase-6 rabbit pAb |
| Alternative Names | CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Caspase 6 (AA range: 223–272) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 35 kD |
| Gene ID (Human) | 839 |
| Human Swiss-Prot No. | P55212 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic acid residues to produce two subunits (large and small) that dimerize to form the active enzyme. This protein is processed by caspases 7, 8, and 10, functioning as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
(RefSeq, Oct 2015)
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