ELK Biotechnology Casein Kinase IIβ rabbit pAb
Casein Kinase IIβ 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 인간 CKII-beta 유래 펩타이드로 면역생성 되었으며, 핵 및 세포질 등 다양한 세포소기관에 존재하는 단백질 검출에 활용됩니다.
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Casein Kinase IIβ rabbit pAb
제품 개요
Casein Kinase IIβ 단백질을 인식하는 rabbit polyclonal antibody입니다. 인간 CKII-beta 유래 합성 펩타이드(AA 166-215)를 면역원으로 생산되었으며, 다양한 종(Human, Mouse, Rat)에 반응합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product Name | Casein Kinase IIβ rabbit pAb |
| Alternative Names | CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/5000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human CKII-beta (AA range: 166–215) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 25 kD |
| GeneID (Human) | 1460 |
| Human Swiss-Prot No | P67870 |
| Cellular Localization | Nucleus, nucleoplasm, cytoplasm, cytosol, plasma membrane, protein kinase CK2 complex, PcG protein complex, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase that regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme comprises three subunits (alpha, alpha prime, and beta) forming a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and Golgi apparatus. Two transcript variants encoding different isoforms have been identified for this gene.
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