
ELK Biotechnology CABC1 rabbit pAb
인간 ADCK3 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 미토콘드리아 단백질 연구에 사용되며, -20°C에서 1년 보관 가능합니다. 다양한 종(Human, Mouse, Rat)에 반응합니다.
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CABC1 rabbit pAb
제품 개요
CABC1 rabbit polyclonal antibody는 인간 ADCK3 단백질(aarF domain-containing protein kinase 3)을 인식하도록 제작된 항체입니다. 미토콘드리아 단백질 연구 및 p53 관련 세포사멸 경로 분석에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | CABC1 rabbit pAb |
| Alternative Names | ADCK3; CABC1; PP265; Chaperone activity of bc1 complex-like; mitochondrial; Chaperone-ABC1-like; aarF domain-containing protein kinase 3 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ADCK3 (AA range: 301–350) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kDa |
| Gene ID (Human) | 56997 |
| Human Swiss-Prot No. | Q8NI60 |
| Cellular Localization | Mitochondrion; Membrane; Single-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. (RefSeq, Jul 2008)
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