ELK Biotechnology C/EBP ζ rabbit pAb
C/EBP ζ rabbit pAb는 인간, 랫, 마우스에서 반응하는 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 세포핵에 위치하며 CEBPZ 단백질을 인식. 세포 성장과 분화 연구 및 AML 관련 연구에 적합.
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제품명
C/EBP ζ rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CEBPZ (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 120 kD |
| GeneID (Human) | 10153 |
| Human Swiss-Prot No | Q03701 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
배경 정보
This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process involving heat shock factors, conserved DNA elements (heat shock elements or HSEs), and CCAAT boxes.
The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner.
It is also involved in cell growth and differentiation, particularly hematopoietic differentiation.
Methylation of the promoter or mutations within the gene may be correlated with the occurrence of acute myeloid leukemia (AML).
[provided by RefSeq, Jun 2016]
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